Annals of African Medicine
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Year : 2022  |  Volume : 21  |  Issue : 3  |  Page : 217-222

An In vitro evaluation of effect of implant abutment on human gingival epithelial keratinocytes

1 Department of Prosthodontics Including Crown Bridge and Implantology, DY Patil Dental School, Lohegaon, Pune, Maharastra, India
2 Department of Preventive Dentistry, College of Dentistry in Ar Rass, Qassim University, Al-Qassim Region, 52571, Kingdom of Saudi Arabia
3 Department of Prosthodontics, Saraswati Dhanwantari Dental College and Research Institute, Perbhani, Maharashtra, India
4 Department of Conservative Dentistry and Endodontics, Sardar Patel Post Graduate Dental and Medical Sciences, Lucknow, Utter Pradesh, India
5 Department of Orthodontics, Former Consultant Max Hospital, Gugaon, India
6 Department of Periodontology, Bharati Vidyapeeth Deemed to be Dental College and Hospital, Navi Mumbai, Maharastra, India
7 Department of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Qassim University, Al Qassim Region, Kingdom of Saudi Arabia

Correspondence Address:
Swaroopkumar M Magar
Department of Prosthodontics, Saraswati Dhanwantari Dental College and Research Institute, Perbhani, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/aam.aam_116_20

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Background: Abutment surfaces are being designed to promote gingival soft tissue attachment and integration. This confirms implant survival for long term by forming a seal around the prosthetics. Objectives: This study was done to compare the biocompatibility of three implant abutments: titanium uncoated, Ti-nitride coated, and modified polyetheretherketone (PEEK) with human gingival keratinocytes. Materials and Methods: The titanium-uncoated, titanium-nitride-coated, and modified PEEK discs (13 mm × 3 mm) were fabricated and compared with uncoated polyester cell culture discs, which were used as controls. These three implant abutments were evaluated for biocompatibility with respect to human gingival keratinocytes for viability, morphology, proliferation, and migration by scanning electron microscopy imaging and scratch wound healing assays. Measurements of roughness show changes between the investigated surfaces. Results: Keratinocytes cultured on all examined surfaces indicated adhesion and attachment. An assay of cell viability showed no substantial variances among the groups. The modified PEEK surface showed greater cell proliferation and migration among the three abutment materials. Conclusion: All three abutment material surface types showed similar epithelial biological responses. However, modified PEEK material showed the highest biocompatibility.

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