Annals of African Medicine
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ORIGINAL ARTICLE
Year : 2022  |  Volume : 21  |  Issue : 2  |  Page : 161-164

Primary hyperparathyroidism: Correlation between cervical ultrasound and MIBI scan


1 Department of Endocrinology, Diabetology and Nutrition, Hospital University Hassan II.Fez; Faculty of Medicine and Pharmacy, Sidi Mohamed Benabdellah University; Laboratory of Epidemiology and Research in Health Sciences, Fez, Morocco
2 Department of Endocrinology, Diabetology and Nutrition; Department of Radiology, Hospital University Hassan II.Fez, Fez, Morocco
3 Department of Radiology, Hospital University Hassan II.Fez; Faculty of Medicine and Pharmacy, Sidi Mohamed Benabdellah University, Fez, Morocco
4 Department of Radiology, Hospital University Hassan II.Fez; Laboratory of Epidemiology and Research in Health Sciences, Fez, Morocco
5 Department of Endocrinology, Diabetology and Nutrition; Department of Radiology; Department of Nuclear Medicine, Hospital University Hassan II.Fez, Fez, Morocco

Correspondence Address:
Houda Salhi
Department of Endocrinology, Diabetology and Nutrition, University Hospital Hassan II, Fez 30000
Morocco
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/aam.aam_73_20

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Introduction: The standard gold treatment of primary hyperparathyroidism (PHP) is parathyroidectomy. Imaging in particular, cervical ultrasound (US) and technetium-99 m- méthoxyisobutylisonitrileparathyroid scintigraphy using the single-photon emission computed tomography (TC-99 m-MIBI-SPECT) are always indicated prior to parathyroid surgery, allowing the location of parathyroid adenomas. The objective of our study is to evaluate the contribution of TC-99 m-MIBI-SPECT and US in the preoperative topographic diagnosis of PHP. Materials and Methods: this is a descriptive and analytical retrospective study, conducted in our department of Endocrinology, Diabetology and Metabolic Diseases in Hassan II University Hospital of Fez between 2009 and 2018. All patients who received a para-thyroidectomy for PHP were recruited. All patients had received a cervical US and a TC-99 m-MIBI-SPECT. We compared imaging data before surgery with data from intraoperative exploration and anatomopathological findings of surgical samples. Results: Forty-eight patients were collected. US correctly identified parathyroid adenoma in 85.40% of patients with PHP versus 89.50% in TC-99 m-MIBI-SPECT. US correctly predicted surgical outecomes in 97.60% of patients and TC-99 m-MIBI-SPECT in 97.72% of cases. Their combination had better results in sensitivity and positive predictive value. Conclusion: TC-99 m-MIBI-parathyroid scintigraphy SPECT had a higher probability for solitary parathyroid adenoma compared to cervical US. Its use coupled with the TC-99 m-MIBI-parathyroid scintigraphy SPECT allows reliable preoperative tracking.


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