| ORIGINAL ARTICLE |
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| Year : 2020 | Volume
: 19
| Issue : 3 | Page : 198-202 |
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Asymptomatic Rotavirus infections among children in Maiduguri, Borno state, Northeast, Nigeria
Monilade T Akinola, Auwalu Uba, Ahmed F Umar, Ediga B Agbo
Department of Biological Sciences, Faculty of Science, Abubakar Tafawa Balewa University (ATBU), Bauchi, Nigeria
Correspondence Address:
Mrs. Monilade T Akinola
Department of Biological Sciences, Faculty of Science, Abubakar Tafawa Balewa University (ATBU), Bauchi
Nigeria
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/aam.aam_55_19
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Background: Rotavirus remains one of the main causative agents of gastroenteritis in young children. This happens, especially in countries (e.g., Nigeria) that have not yet introduced the vaccine into the national immunization program. A significant prevalence of Rotavirus infection both in children and adults without major symptoms has earlier been reported. This study aimed at defining the prevalence of asymptomatic Rotavirus infection from apparently healthy children in Maiduguri, Borno State, Northeastern Nigeria. Methods: A total of 269 stool samples were randomly collected from apparently healthy children <15 years of age from July 2017 to June 2018. All samples were screened using a commercially available enzyme-linked immunosorbent assay kit for the presence of Rotavirus antigen. The Rotavirus-positive samples were further subjected to polyacrylamide gel electrophoresis (PAGE) to determine their RNA electropherotypes. Results: A total of 59 stool samples (19.9%) were Rotavirus positive with peaks observed in the cold dry season, among male children, and 6–10 years of age group. A total of 50 randomly selected Rotavirus-positive samples were subjected to PAGE, and none of the samples showed either long or short profiles. Conclusion: This study shows that Rotavirus can be shed into environments without any signs and symptoms. In view of this, the Rotavirus vaccine should be considered a priority and be introduced in the existing national immunization program in Nigeria, particularly in Borno State.
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