Annals of African Medicine
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Year : 2016  |  Volume : 15  |  Issue : 2  |  Page : 83-86

Co-existing autosomal dominant polycystic kidney disease and nephrotic syndrome in a Nigerian patient with lupus nephritis

1 Kidney Care Centre, University of Medical Sciences, Ondo State, Nigeria
2 Department of Radiology, Trauma Centre, University of Medical Sciences, Ondo State, Nigeria
3 Department of Morbid Anatomy, Centre University of Medical Sciences, Ondo State, Nigeria
4 Department of Morbid Anatomy, University of Medical Science, Ondo State, Nigeria

Correspondence Address:
A A Akinbodewa
PMB 542, Medical Village, 23434 Ondo Township, Ondo State
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1596-3519.179735

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A little over 30 cases on co-existing nephrotic syndrome and autosomal dominant polycystic kidney disease (ADPKD) have been reported from different regions of the world since 1957. We present a case report on co-existence of nephrotic syndrome (secondary to lupus nephritis) with ADPKD in a 24-year-old woman from Nigeria. She was positive for anti-double stranded DNA. Renal histology showed International Society of Nephrology/Renal Pathology Society Class II lupus nephritis. The co-existence of nephrotic syndrome and ADPKD may have been overlooked in Africa in the past. There is a need to screen for nephrotic syndrome in patients with ADPKD among clinicians in the African setting.

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