|LETTER TO THE EDITOR
|Year : 2015 | Volume
| Issue : 3 | Page : 160-161
Thiopentone sodium and propofol for facilitation of laryngeal mask airway insertion
Nora Pokee1, Viroj Wiwanitkit2
1 Pokee-Clinic, Bangkok, Thailand
2 Joseph Ayobabalola University, Akure, Nigeria
|Date of Web Publication||28-May-2015|
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Pokee N, Wiwanitkit V. Thiopentone sodium and propofol for facilitation of laryngeal mask airway insertion. Ann Afr Med 2015;14:160-1
Sengupta and Sengupta compared between thiopentone sodium and propofol for facilitation of laryngeal mask airway insertion and reported "residual intact upper airway reflexes can be easily suppressed when propofol (2.5 mg/kg) is used as an inducing agent with adequate oxygen inhalation and can be suggested beneficial compared with thiopentone alone in managing the airway. " In fact, this report can address the clinical usefulness of propofol. However, there are some interesting unwanted effects of propofol that should not be forgotten. Marik noted "high dose propofol infusions have been associated with the "propofol syndrome"; this is a potentially fatal complication characterized by severe metabolic acidosis and circulatory collapse. " In general, it is suggested to reduce the dosage of propofol as much as possible. For laryngeal mark airway insertion, to reduce the dosage of propofol, some modifications are proposed. A good example is using propofol combining with seroflurane.  It is reported that sevoflurane-propofol method can significantly reduce the problem of apnea comparing to using propofol along. 
| References|| |
Sengupta J, Sengupta M, Nag T. Agents for facilitation of laryngeal mask airway insertion: A comparative study between thiopentone sodium and propofol. Ann Afr Med 2014;13:124-9.
Marik PE. Propofol: Therapeutic indications and side-effects. Curr Pharm Des 2004;10:3639-49.
Siddik-Sayyid SM, Aouad MT, Taha SK, Daaboul DG, Deeb PG, Massouh FM, et al.
A comparison of sevoflurane-propofol versus sevoflurane or propofol for laryngeal mask airway insertion in adults. Anesth Analg 2005;100:1204-9.