Pilot study on multidrug resistant tuberculosis in Nigeria

L Lawson; AG Habib; MI Okobi; D Idiong; I Olajide; N Emenyonu; N Onuoha; LE Cuevas; SO Ogiri

doi:10.4103/1596-3519.68355

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Year : 2010 | Volume : 9 | Issue : 3 | Page : 184-187

Pilot study on multidrug resistant tuberculosis in Nigeria

L Lawson¹, AG Habib², MI Okobi³, D Idiong¹, I Olajide¹, N Emenyonu¹, N Onuoha¹, LE Cuevas⁴, SO Ogiri⁵
¹ Zankli Medical Centre, Plot 1021 Shehu YarAdua Way, Abuja, Nigeria
² Department of Medicine, Aminu Kano Teaching Hospital, PMB 3452, Kano; Institute of Human Virology Nigeria (IHVN), Abuja, Nigeria
³ Wuse General Hospital, Abuja, Nigeria
⁴ Liverpool School of Tropical Medicine, Liverpool, United Kingdom
⁵ World Health Organization (WHO), Liaison Office, PMB 208, Minna, Nigeria

Correspondence Address:
A G Habib
Department of Medicine, Aminu Kano Teaching Hospital, PMB 3452, Kano
Nigeria

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/1596-3519.68355

Background: Drug resistant tuberculosis (TB) has lately emerged and it represents a serious public health problem. We set out to determine drug resistance among TB patients. Methods: Using automated BACTEC cultures, multidrug resistant-tuberculosis (MDR-TB) was investigated in 117 diagnosed cases in Abuja, Nigeria. Results: Ten (31%) of 32 culture-positive patients were resistant to at least one and four (13%) to all of the four drugs tested. No association between drug resistance and human immunodeficiency virus (HIV) infection was found. Conclusions: MDR-TB is present in Nigeria and larger studies are urgently required. TB clinical management and control efforts should be improved.

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